Predictive factors of ovarian response to GnRH antagonist stimulation protocol: AMH and age are potential candidates

Abstract Background Prediction of ovarian response prior to the stimulation cycle is useful in determining optimal starting dose recombinant follicle-stimulating hormone (r-FSH). This study was designed (I) evaluate which following parameters (age, AMH, and FSH) can be used as a predictor GnRH antagonist protocol, (II) determine cutoff value AMH age for predicting poor high response, (III) investigate relationship between age, level, other clinical parameters. It retrospective study. A total 318 women with mean 28.2 ± 5.9 years old were included this Hormone levels (FSH, LH, PRL, E2, AMH) number collected oocytes determined. Based on retrieved oocytes, participants divided into three groups: (oocytes < 4, n = 51), normal 4–14, 192), > 14, 75). Results significant increase has been found level mature from low group ( P 0.001). Also, significantly greater than groups positive correlation The receiver operating characteristic (ROC) curves showed that both had highest accuracy prediction 1.45 31.5 years, respectively. Additionally, ROC analysis shown accuracy, followed by 3.55 27.5 Conclusions demonstrates women’s may potential predictors protocol.